According to a report prepared by the EAFIT University and the Pro Antioquia organization, during the pandemic more than 40% of the economically active population of the Department of Antioquia could not work. Thus, more than 1,172,410 jobs were affected. The economic losses exceed the figure of 1.9 billion Colombian pesos. Unemployment has mainly affected the manufacturing, construction, food services, hospitality and tourism sectors. It should be noted that Medellín was one of the first cities in Colombia to begin to open the economy to some sectors, with strict controls and protections of citizen bio-safety. Additionally, those living in the city will notice that mask usage among the local population remains very high.